摘要
目的探讨反复流产与染色体核型异常的关系。方法对女方有反复流产史的夫妇进行外周血淋巴细胞的染色体核型分析。结果268例夫妇中染色体核型异常者31例,其中,大Y有14例,常染色体多态性8例,平衡易位4例,倒位3例,插入1例,及47,XXY 1例。结论夫妻双方中有一方染色体异常,都可导致女方反复流产,反复流产的夫妇应进行染色体检查。
Objective： To explore the relationship between RSM and abnormal karyotypes. Method： Karyotype the peripheral blood lymphocytes chromosomes of couples with RSM. Results： 268 couples with RSM underwent cytogenetic examination in which 31 persons were found with abnormal karyotypes, including 14 cases with large Y chromosome, 8 with autosomatic heteromorphism, 4 with balanced translocation, 3 with inversion, 1 with insertion, and 1 with 47, XXY. Conclusion： RSM can occur when either of the couples has abnormal karyotypes, and karyotyping are suggested for RSM.
出处
《中国优生与遗传杂志》
2009年第9期49-50,共2页
Chinese Journal of Birth Health & Heredity
关键词
自然流产
染色体
核型
Recurrent spontancous micarriage
Karyotype
