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血管生成素-2和内皮抑素在子宫内膜异位症患者血清和腹腔液中的表达及意义

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摘要 目的探讨血管生成素-2和内皮抑素在子宫内膜异位症血管生成中的作用。方法采用酶联免疫吸附测定法检测30例内异症患者腹腔液和血清中血管生成素-2及内皮抑素的蛋白含量并与对照组相比较。结果内异症组血清和腹腔液中Ang-2、ENS含量及Ang-2/ENS比值均高于对照组,P<0.05,差异有统计学意义。结论1.盆腹腔的血管生成活性可能强于远处组织和器官,利于逆流入腹腔的子宫内膜碎片的种植。2.内异症的血管生成取决于多种因子间的相互协调,当血管生成的动态平衡被打破,正性血管调节因子Ang-2在总体上处于主导地位时。
出处 《中国优生与遗传杂志》 2009年第9期72-74,共3页 Chinese Journal of Birth Health & Heredity
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