161例眼眶内容物摘除术的病因分析

Clinical and pathological analysis of 161 cases of orbital exenteration

目的探讨眼眶内容物摘除术的病因。方法回顾性分析1981年1月～2007年12月行眼眶内容物摘除术的161例（161眼）患者的病例资料，其中男94例，女67例；年龄2～82岁，分析其原因。结果161例眼眶内容物摘除术中，46例眼眶原发性肿瘤、110例眼眶继发性肿瘤和5例非肿瘤性病变。共有26种病理类型，主要包括视网膜母细胞瘤（RB）67例，恶性黑色素瘤20例，鳞状细胞癌12例，腺样囊性癌10例。按原发病变部位位于眼球者81例，眼眶者51例，结膜者15例，眼睑者11例，鼻咽及副鼻窦者3例。结论眼眶原发性恶性肿瘤和继发性恶性肿瘤是眼眶内容物摘除术的主要原因。

Objective Different study reports on cause of orbital exenteration were published in abroad, However,the large sample of case analysis of cause of orbital exenteration is still sandom in China. This study was to survey the causes of orbital exenteration. Methods This was a retrospective study. The clinical and pathological data of 161 patients undergone orbital exenteration from January, 1981 to December,2007 at the West China Hospital were analyzed. 161 patients were identified in this survey. The age of patients was from 2 years to 82 years. Ninety-four patients were males and sixty-seven cases were females. Results In 161 eyes of 161 cases,46 eyes were primary orbital tumor,and 110 eyes were secondary orbital tumor and 5 eyes of 5 cases were non-tumor diseases. Twenty-six different pathological types were encountered in this survey. The most common diseases included retinoblastoma （ 67/161 ） , melanoma （ 20/161 ） , squamous cell carcinoma （ 12/161 ） and adenoid cystic carcinoma（ 10/161 ）. The 81 primary lesions were located in eyeball,51 in orbit, 15 in conjunctiva, 11 in eyelid and 3 in nasal pharynx and nasal affixed sinus. Conclution The main causes for orbital exenteration are primary and secondary malignant orbital tumors.