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肝卵圆细胞及其定向诱导分化为胰岛细胞的相关研究

Research progress of hepatic oval cells and differentiation into pancreatic cells
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摘要 胰岛细胞移植是治愈糖尿病的可能方法,但胰岛细胞数量有限,不能满足临床需要。肝卵圆细胞可以在体外诱导分化为胰岛细胞,因此可以作为胰岛细胞潜在的替代资源。文章就肝卵圆细胞及其定向诱导分化为胰岛细胞的相关研究作一综述。 Islet cell transplantation is a possible method to cure diabetes mellitus. However, the limited islet resources can not meet the clinical requirement. Hepatic oval cells can be induced in vitro to differentiate into pancreatic cells, and can sever as a potential alternative resource. This article reviews the research progress of hepatic oval cells and differentiation into pancreatic cells.
作者 赵丽娟 陆颖理
机构地区 上海交通大学医学院第九人民医院内分泌代谢科
出处 《上海交通大学学报（医学版）》 CAS CSCD 北大核心 2009年第8期997-1000,共4页 Journal of Shanghai Jiao tong University:Medical Science
关键词 肝卵圆细胞 胰岛细胞 活化 增殖 分离 纯化 鉴定 诱导分化 hepatic oval ceils pancreatic cells activation proliferation separation purification identification induction and differentiation
分类号 Q813 [生物学—生物工程] R587.1 [医药卫生—内分泌]
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参考文献29

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上海交通大学学报（医学版）
2009年 第8期

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