乙酸对甲苯酚酯的合成工艺研究

Study on Synthesis of p-Cresyl Acetate

以乙酰氯和对甲苯酚为原料合成了乙酸对甲苯酚酯,考察了反应温度、反应时间、原料配比等对合成反应的影响,确定了乙酸对甲苯酚酯的最佳合成工艺条件:反应温度40℃,反应时间7 h,n(对甲苯酚):n(乙酰氯)=1:1.5;乙酸对甲苯酚酯的收率可达94.95%,产品纯度达98.5%以上。

p- Cresyl acetate was synthesized with acetyl chloride and p -cresol as materials. The effects of reaction temperature, reaction time and material ratio on the synthesis were studied. The optimum synthesis condition was determined as follows： reaction temperature was 40 ℃, reaction time was 7 h, n（p -cresol）： n（acetyl chloride） was 1： 1.5. The yield ofp -cresyl acetate was up to 94.95%. The purity of the product was over 98.5%.