子宫内膜异位症恶变倾向及处理

Management of the tendency toward malignant transformation of endometriosis

子宫内膜异位症(内异症)是一种良性病变,但具有类似于恶性肿瘤的生物学行为,且具有恶变倾向。内异症恶变率为0.7%～1.0%,以卵巢内异症恶变多见。现认为内异症恶变倾向可能与激素、病程、年龄以及月经婚育史有关。目前,对于内异症恶变的治疗以手术治疗为主,辅以化疗、放疗及孕激素等综合治疗。对于有内异症恶变倾向的患者行剖腹探查术,以求做到早诊断,早治疗。

Endometriosis is a benign disorder, but it shows some characteristics of malignancy and has a tendency toward malignant transformation. The risk of endometriosis malignant is between 0.7% and 1.0% , in which endometriosis of the ovary is predominant. It is recently reported that the tendency of malignant transformation of endometriosis can be related to hormone, disease progress, age and menstrual and obstetrical history. The current treatment of endometriosis malignancy mainly focuses on surgery, and is aided with comprehensive treatments by chemotherapy, radiation treatment and hormone therapy. To the patient who has the tendency of endometriosis malignancy, exploratory laparotomy should be operated to achieve early diagnosis and treatment.