单模聚焦微波辐射合成甲基丙烯酸甲酯

Synthesis of Methyl Methacrylate With Single-Mode Focus Microwave Radiation

采用Discover微波精确有机合成系统及其单模聚焦微波辐射技术、空压气体同步冷却技术,以2-甲基丙烯酸和甲醇为原料,以硫酸为酯化反应的催化剂,以对苯二酚为阻聚剂,研究了甲基丙烯酸甲酯(MMA)的合成。在Discover微波精确有机合成系统的标准模式下,对反应物物质的量比、辐射功率、反应时间等因素进行了考察。实验结果表明,微波加热最佳的反应条件是:反应温度为70℃,2—甲基丙烯酸与甲醇的物质的量比为1∶2,功率为100 W,反应时间为30 min,收率为88%。

The methyl methaerylate （MMA） was synthesized by precision microwave organic synthesis system and its single-mode focusing microwave radiation technology, synchronized Pneumatic gas cooling technology. In the experiment, 2-methyl acrylate and methyl alcohol were used as materials, sulphuric acid as a catalyst for esterification, and hydroquinone as a polymerization inhibitor. Under Discover precision microwave organic synthesis system standard mode, the mol ratio of reaction, the reaction power, the reaction time, and other factors were investigated. The experimental results show that the optimal conditions of microwave heating are as follows.. The reaction temperature 70℃, the ratio of 2- methyl acrylate and methyl alcohol 1 ： 2, the power 100W, the reaction time 30 min, the yield 88%.