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定量检测大肠良恶性病变ras p21、CEA的临床价值 被引量:1

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摘要 ras基因编码p21蛋白,其基因突变导致基因激活,具有使细胞癌变的能力。CEA可作为大肠癌的抗原标记。定量检测大肠癌变p21、CEA,有理论意义及早期诊断价值。1材料与方法1.1大肠活检标本癌67例(高分化管状腺癌25例,低分化腺癌23例,印戒细胞癌...
机构地区 内蒙古医学院
出处 《中国肿瘤临床》 CAS CSCD 北大核心 1998年第9期680-681,共2页 Chinese Journal of Clinical Oncology
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同被引文献15

  • 1张旭晨,赵凤志,戴欣,鲁香凤,魏福德,张晓露,郭琳,葛桂苓.实验性胃癌前期病变大鼠胃粘膜电镜观察[J].电子显微学报,1994,13(5):417-417. 被引量:2
  • 2张旭晨,赵凤志,代欣,鲁香风,卜益民.综合法复制大鼠胃癌前期病变模型[J].中华实验外科杂志,1994,11(5):311-312. 被引量:20
  • 3张旭晨,赵凤志,代欣,鲁香凤,古雪迎,方杰.消痞灵冲剂对实验性胃癌前期病变大鼠胃粘膜胃螺旋样菌感染的防治作用[J].北京中医药大学学报,1995,18(4):59-62. 被引量:17
  • 4Moil M, et al. Prognostic value of immunohistochemically identified CEA, SC, AFP and S- 100 protein positive cells in gastric cancer. Cancer 1988; 62:534.
  • 5Kojima O, et al. Correlation between carcinoembryonic antigen in gastric cancer tissue and survival of patients with gastric cancer. Gann 1984; 75:230.
  • 6Nitfi D, et al. Carcinoembryonic antigen in gastric juice collected during endoscopy, its value in detecting high risk patients and gastric cancer. Cancer 1983 ; 52 : 2234.
  • 7Marrelli D, et al. Prognostic significance of CEA, CA 19 - 9 and CA 72-4 preoperative serum levels in gastric carcinoma.Oncology 1999 ; 57 ( 1 ) : 55.
  • 8Imada T, et al. Serum CA 19 - 9, SLX, STN and CEA levels of the peripheral and the draining venous blood in gastric cancer. Hepatogastroenterology 1999; 46 (27) :2086.
  • 9Kasper HU, et al. P21 protein expression and ras-oncogene mutations in gastric carcinoma: correlation with clinical data.Int J Oncol 1998; 12 (1) :69.
  • 10Tahara E, et al. Ha- ras oncogene product in human gastric carcinoma: correlation with invasiveness, metastasis or prognosis. Jpn J Cancer Res 1986; 77 (6) :517.

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