兔颞下颌关节盘移位与骨关节病关系的评价

Evaluation in the relationship of disc displacement of temporomandibular joint to osteoarthrosis in the rabbit

目的评价颞下颌关节盘移位与骨关节病的关系。方法通过手术方法将２５只大耳白兔的颞下颌关节盘前移，术后１、２、４、８、１２周进行组织病理学检查。结果１１侧手术关节为部分关节盘前移位，８侧为完全性关节盘前移位，６侧为关节盘穿孔。部分关节盘前移位出现早期退行性改变和后期生理性改建，完全性关节盘前移位和关节盘穿孔出现退行性改变和严重的骨关节病。结论颞下颌关节盘前移位的程度与骨关节病有关，关节盘前移位越明显。

Objective The purpose of this study, using an animal model, was to evaluate the relationship between disc displacement of temporomandibular joint (TMJ) and osteoarthrosis.Methods The disc was surgically displaced anteriorly in the right TMJ in each of 25 rabbits. The TMJs were removed after 1,2,4,8 and 12 weeks and stained with H&E.Results 11 joints had partial anterior disc displacement, 8 joints with complete anterior disc displacement and 6 joints with perforation. The partial anterior disc displacement joints showed early degenerative or physiologic remodeling changes, the complete anterior disc displacement and perforation joints showed degenerative or severe osteoarthritic changes.Conclusion The degree of anterior disc displacement of TMJ relates to the osteoarthrosis. The farther anteriorly, the more easily disc displacement can cause the osteoarthrosis.