核素造影评价生长激素缺乏症者左心室功能

Evaluation of Left Ventricular Function in Juvenile Patients with GHD by Radionuclide Angiography

为了评价生长激素缺乏症(GHD)患者左心室功能,用平衡法核素心室造影测定了35例儿童期生长激素缺乏症患者左心室收缩与舒张功能。结果:40%GHD 患者左心室整体收缩功能低下,其中81%为左心室局部收缩功能受损,舒张功能低下的阳性率为45.7%。结论:局部收缩功能异常早于舒张功能异常,而舒张功能异常则又早于整体收缩功能异常。因此,对儿童 GHD 患者应尽早检测心功能,以预防成年后心血管疾病的发生。

To evaluate the left-ventricular function of the juvenile patients with GHD,we studied the left-ventriclular systolic and diastolic function in 35 cases of GHD patients by equilibrium radionuclide angiography.The study shows that 40 % of the patients had left-ventricular global systolic dysfunction,among them,the percentage of the patients whose regional systolic function was damaged was 81%,45.7 % of the patients had diastolic dysfunction.The results indicated that the regional systolic dysfunction appeared prior to the diastolic dysfunction.However,the diastolic dysfunction appeared prior to the global systolic dysfunction.We conclude that the test of left-ventricular function should be performed in the patients with GHD as early as possible to prevent the occurrence of the cardiovascular disease after the maturity.