33例不育症病人抗心磷脂抗体的研究

Study on anticardiolipin antibodies (ACA) in patients with recurrent abortion

目的 :为了研究不育症的病因、发病机理 ,提供临床诊断依据。方法 :利用酶联免疫吸附(ELISA)法 ,对 33例不育症病人进行了抗心磷脂抗体 (ACA)的 Ig G、Ig M的血清学检测。结果 :不育症病人组的血清 Ig G- ACA和 Ig M- ACA显著高于正常对照组的 Ig G- ACA和 Ig M- ACA水平。结论

Objective:In order to investigate the pathogenesis and the pathologic physiological mechanisms and to provide experimental data for clinical diagnosis.Methods:ACA were determined in 33 recurrent abortion patients and 40 controls by an enzyme linked immunosorbent assay.Results:The results showed that IgG-ACA and IgM-ACA in patients were higher than those of control ( P <0 05).The ACA positive rate of recurrent abortion group was 21.2%.Among them,only positive IgG-ACA occurred in 5 patients,both positive IgG-ACA and positive IgM-ACA in 2 patients,and positive IgM-ACA in 1 patient.Conclusion:These results suggest that ACA has some relation with the recurrent abortion.