48例子宫肌瘤介入治疗的中长期疗效评价

Curative effect of interventional uterine arterial embolization therapy in the treatment of 48 patients with hysteromyoma

目的:评价以PVA颗粒及明胶海绵颗粒作为栓塞剂对子宫动脉进行栓塞治疗子宫肌瘤的可行性和有效性。方法:采用回顾性研究方法,对48例接受双侧子宫动脉栓塞治疗的子宫肌瘤患者进行临床观察及术后随访,评价该法的安全性及有效性。结果:所有病例术后随访3-12月。术后3月、6月及12月临床症状改善率分别为85%、89%和94%。术后3月、6月及12月肌瘤平均缩小率为24.1%、50.0%和68.1%。术后12月子宫体积平均缩小率为63.8%。48例患者术后均无严重并发症。结论:对于想保留子宫的年轻女性,或不原接受手术治疗的子宫肌瘤患者,以PVA颗粒及明胶海绵颗粒作为栓塞剂的子宫动脉栓塞术是一种安全有效的微创治疗手段,值得推广。

Objective：To evaluate the safety and curative effect of transcatheter uterine arterial embolization in treatment of hysteromyoma with PVA granules and absorbable gelatine sponge granules. Methods ： To retrospectively study 48 patients with hysteromyoma treated by transcatheter uterine arterial embolization. These patients were followed up for 3 to 12 mouths postoperatively. Results： The symptom improved rates after operation 3 months,6 months and 12 months were 85% ,89% and 98% , respectively. The sizes of hysteromyomas were lessened, with rates of 24.1% ,50.0% and 68.1% respectively after these periods, and the average rate was 63.8%. The clinical symptoms were improved and without severe complications postoperatively. Conclusion： It is an safe and effective method to treat hysteromyoma by using transcatheter uterine arterial embolization with PVA granules and absorbable gelatine sponge granules, especially to patients who want to preserve their uteruses or are unwilling to receive surgical resection.