外阴疣状癌3例并文献复习

Verrucous carcinoma of vulva

目的:探讨外阴疣状癌的发病因素、临床表现、诊断及治疗。方法:回顾分析我院自1989年至今共收治3例外阴疣状癌的临床资料,并结合文献进行探讨。结果:3例疣状外阴癌均为老年,均来自经济落后、卫生条件较差的地区,且早婚、早育、多产,3例都通过2次以上活检确诊。其中2例手术治疗效果较好,术后才确诊为外阴疣状癌,1例第二次活检确诊为外阴疣状癌,放弃治疗死亡。结论:外阴疣状癌临床过程长,远处转移较少,预后较好,临床可疑病例应尽早活检,临床检查与病理结果不相符时建议活检组织要够深,防止误诊。必要时可多次活检以免漏诊。

Objective： To investigate the etiological factor, cilinical manifestation, and treatment of verrucous carcinoma in vulva. Methods： Cilinical data of 3 caseas treated in our hospital from 1989 were retrospectively analysed. Results： All 3 patients of verrucous carcinoma in vulva occured in elderly, poor economic, and poor health condition area. All of them were early married, early gravited, and copiousness ; 3 caseas were diagnosed by two times of biopsy. Two cases were effectivly treated with surgery ,and diagnosis confirmed after operation,another one was confirmed by two times of biopsy, gave up treatment and died. Concolusion： The cilinical course of verrucous carcinoma in vulva is long with less distant matastesis, and good prognosis, so patients suspected in clinic shoud be examined by biopsy as soon as possible, deeper biopsy sometimes is useful, multiple biopsy is required if necessary.