余肺切除术治疗再发非小细胞肺癌44例

Completion pneumonectomy for recurrent non-small cell lung cancer：experience with 44 cases

目的探讨余肺切除术治疗再发非小细胞肺癌的手术适应证、手术方式和预后。方法回顾性分析肺癌再发行余肺切除术病人44例资料，采用Kaplan-Meier法计算余肺切除术后病人的1、3和5年生存率。并对相关因素进行分析。结果围手术期死亡1例。余肺切除术后1、3和5年的生存率分别为72．73％、26．22％和18．98％。两次手术间隔时间对余肺切除术后的生存率有明显影响（P=0．019）。结论余肺切除是一项复杂的手术操作，但是经过合理选择病例，仍可取得比较满意的效果。

Objective To evaluate the indications, operative technique and result of completion pneumonectomy for recurrent non-small cell lung eancer（NSCLC）. Methods From January 1998 to December 2006, 44 patients with NSCLC underwent completion pneumonectomy for their local recurrence. The 1-, 3- and 5- year survival rates were calculated by Kaplan-Merier methods and the risk factors for survival were analysed. Results There was 1 patient died postoperatively with hospital mortality rate of 2.27%. The 1-, 3- and 5- year survival rates were 72.73%, 26.22% and 18.98% ,respectively. The median interval between two operations was the important risk factor for survival after the completion pneumonectomy. Condusion Completion pneumonectomy for recttrrent NSCLC is a safe surgical procedure and the long-term survival is acceptable though it has a relatively high mortality and morbidity.