儿童沙门氏菌属的耐药性变异和抗生素的合理选用

Resistant Salmonella Strains in Pediatric Patients and Reasonably Using Antibiotics

对湖州市第二医院儿科1991～1996年送检标本经分离、鉴定得到的沙门氏菌属178株,采用K-B法进行12种抗生素药敏试验。结果显示,上述菌株对复方新诺明、苯唑青霉素的耐药率已很高,且各年度菌株对氨苄青霉素及复方新诺明的耐药率差异有显著性和非常显著性(P<0.05,P<0.01)。临床应根据细菌耐药情况合理选用抗生素,减慢细菌耐药性变异。

In 1991 ~ 1996,178 strains of salmonella were isolated from pediatric patients and were tested by K-B method to identify their antibiotic susceptibility with 12 common antibacterial agents. The results showed that most of these strains were resistant to sulfamethoxazole compound and oxacillin,and the resistant strains rate was increasing year by year. Therefore,antibiotics should be used reasonably in order to slow down the increasing rate of resistant strains of salmonella.