摘要
目的:探讨扁桃体癌放射治疗的疗效及预后因素。方法:回顾性分析107例经病理证实的扁桃体癌患者的临床病理资料,均行单纯根治性放射治疗。Ⅰ期5例,Ⅱ期14例,Ⅲ期27例,Ⅳ期61例。生存分析采用Kaplan-Meier法及Logrank检验,多因素分析采用Logistic回归模型。结果:全组5年总生存率为45.8%。Ⅰ期-Ⅳ期5年生存率分别为89.6%、72.2%、54.3%和38.9%。多因素分析显示UICC分期为主要的预后因素。结论:UICC分期为扁桃体癌的主要的预后因素,单纯放射治疗对Ⅰ、Ⅱ期扁桃体癌病变可取得较好的疗效。
Objective: To evaluate the therapeutic outcome and define the prognostic factors in patients with tonsiUar carcinoma after radical radiotherapy. Methods: 107 patients with pathologically confirmed tonsillar carcinoma were treated with radical radiotherapy. According to TNM staging system, there were 5 Stage Ⅰ , 14 Stage Ⅱ 27 Stage Ⅲ and 61 StageⅣ patients. The significance of prognostic variables in the survival expectancy was evaluated with multivariate analysis and Cox stepwise regression model. Results: The 5-year total survival rates were 45.8%. The 5-year survival rates base Ⅳ. Multivariate analysis showed that UICC stages were the significant prognostic factors. Conclusion: Radiotherapy is an effective way to treat tonsillar carcinoma, especially for Stage Ⅰ and Ⅱ patients who are likely to give good results.
出处
《肿瘤预防与治疗》
2009年第2期173-175,共3页
Journal of Cancer Control And Treatment
关键词
扁桃体肿瘤
放射疗法
预后
Tonsillar Carcinoma
Radiotherapy
Prognosis