围手术期抗菌药物应用调查分析

Antibiotics Application in Perioperative Period:An Investigation

目的了解与分析外科系统围手术期抗菌药物预防性使用情况,对围手术期抗菌药物的合理使用和宏观管理提供科学依据。方法以药物选择、用法用量、首剂给药、疗程、清洁手术抗菌药物应用率为评价指标,评价某院外科手术预防应用抗菌药物的合理水平。结果抗菌药物使用率100.0%;术前30min给药占4.1%,而术前未给药占73.2%;术后用药≤3d占8.1%;三代头孢菌素占全部用药的49.0%,喹诺酮类药物占全部用药的25.0%。结论抗菌药物在围手术期的预防性应用还存在一些问题,有必要规范抗菌药物的应用。

OBJECTIVE To analyze the prophylactic application of antibiotics during perioperative period in surgical department and provide the scientific basis for management and rational application of antibiotics. METHODS The rational use of antibiotics during perioperative period was evaluated based on antibiotics selection, usage, dosage, the first time of application, treatment course, and the percentage of antibiotic application for cleaning operation. RESULTS All of surgical operations were used antibiotics. As for the first time of application, the use rate of thirty minutes before operation was 4.1%, but nothing used before operation was 73.2%. The treatment period after operation within 3 days was 8.1%. Among all kinds of used antibiotics, the third generation of cephalosporin accounted for 49X, and quinolones for 25%. CONCLUSIONS There are still some problems about prophylactic application of antibiotics during perioperative period in surgical department in our hospital. It is necessary to standardize application of antibiotics during perioperative period.