1447例容桂社区老年人下肢动脉疾病的流行病学调查

Prevalence of lower extremity arterial disease in 1 447 old residents in Rong-gui community

目的了解顺德容桂街道60岁以上老年人下肢动脉疾病(lower extremity peripheral arterial disease,LEAD)的流行病学调查情况。方法对顺德容桂街道整群随机抽取2个村。共调查1447例常住老年人,根据有无LEAD分为LEAD组(165例)和无下肢动脉疾病(NLEAD)组(1 282例),调查内容包括一般临床资料、血脂、空腹血糖、腰围、臀围,计算出体重指数、腰臀围比和腰围身高比,测量四肢血压,计算出踝肱指数和趾肱指数。结果LEAD组与NLEAD组在年龄、性别、吸烟、收缩压(SBP)、舒张压(DBP)、空腹血糖、原发性高血压和糖尿病等方面差异有统计学意义。LEAD组与NLEAD组男性在年龄、SBP、DBP、原发性高血压和糖尿病等方面差异有统计学意义。LEAD组与NLEAD组女性在年龄、吸烟、SBP、DBP、空腹血糖、原发性高血压和糖尿病等方面差异有统计学意义。多因素logistic回归分析.预测总人群LEAD风险的因素是年龄、SBP、吸烟、腰围、糖尿病;预测男性LEAD风险的因素是SBP;预测女性LEAD风险的因素是年龄、SBP、吸烟。结论预测老年人LEAD风险的因素可能是年龄、SBP、吸烟、腰围、糖尿病。

Objective To investigate prevalence of lower extremity arterial disease（LEAD） in residents aged ≥60 years in Rong-gui community, Shunde district. Methods Residents aged ≥60 years（1 447 persons） in 2 villages were randomly exampled in Rong-gui community. They were divided into LEAD group（165 persons）and non-LEAD（NLEAD） group（1 282 persons）. Investigative items included common clinical data,blood lipid,fasting plasma glucose（FPG）,waist circumference（WC）, hip circumference, blood pressure of four limbs, body mass index, waist hip ratio, waist height ratio, ankle-brachial index and toe-brachial index. Results The differences of age, sex,smoking, SBP, DBP, FPG, history of primary hypertension and diabetes rnellitus between NLEAD group and LEAD group had statistical significance. The differences of age, SBP, DBP, his- tory of primary hypertension and diabetes mellitus had statistical significance in male group. The differences of age, smoking, SBP, DBP, FPG, history of primary hypertension and diabetes mellitus had statistical significance in female group. Logistic regression analysis showed that the factors, such as age, smoking,SBP,WC, history of diabetes mellitus appeared to be independent risk factors for LEAD in whole group,SBP was the risk factor in male group,age,SBP and smoking were risk factors in female group. Conclusion The risk factors for LEAD appear to be age, smoking, SBP,WC and history of diabetes mellitus.