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文拉法辛治疗SSRIs无效广泛性焦虑症效果观察

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摘要 目前用于广泛性焦虑治疗的药物除苯二氮卓类外,最常用的是选择性5-羟色胺重吸收抑制剂(SSRIs),然而临床上仍有部分患者对SSRIs或SSRIs联合苯二氮革药无效或部分有效。文拉法辛为5-羟色胺及去甲肾上腺素的再摄取抑制剂,国内外文献报道其治疗广泛性焦虑有效。我们应用文拉法辛治疗对SSRIs无效的广泛性焦虑,并与三环类抗抑郁药氯米帕明进行对照,以观察文拉法辛对SSRIs治疗无效广泛性焦虑的疗效及安全性。
出处 《浙江医学》 CAS 2009年第2期228-229,共2页 Zhejiang Medical Journal
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