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瘦素的免疫调节作用研究进展 被引量：4

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作者 裘辉 梁华平
机构地区 第三军医大学大坪医院野战外科研究所一室创伤烧伤与复合伤国家重点实验室
出处 《重庆医学》 CAS CSCD 北大核心 2009年第18期2365-2367,共3页 Chongqing medicine
基金 国家重点基础发展规划项目(2005CB522602)
关键词 瘦素 免疫调节
分类号 R589.2 [医药卫生—内分泌] R392.6 [医药卫生—免疫学]
  • 相关文献

参考文献21

  • 1Claycombe K,King LE,Fraker PJ.A role for leptin in sustaining lymphopoiesis and myelopoiesis[J].Proc Natl Acad Sci USA,2008,105(6):2017.
  • 2Palmer G,Aurrand-Lions M,Contassot E,et al.Indirect effects of leptin receptor deficiency on lymphocyte populations and immune response in db/db mice[J].J Immunol,2006,177(5):2899.
  • 3Hick RW,Gruver AL,Ventevogel MS,et al.Leptin selectively augments thymopoiesis in leptin deficiency and lipopolysaccharide-induced thymic atrophy[J].J Immunol,2006,177(1):169.
  • 4Sennello JA,Fayad R,Pini M,et al.Transplantation of wild-type white adipose tissue normalizes metabolic,immune and inflammatory alterations in leptin-deficient ob/ob mice[J].Cytokine,2006,36(5-6):261.
  • 5Mansour E,Pereira FG,Araujo EP,et al.Leptin inhibits apoptosis in thymus through a janus kinase-2-independent,insulin receptor substrate-1/phosphatidylinositol-3 kinase-dependent pathway[J].Endocrinology,2006,147(11):5470.
  • 6Mancuso P,Huffnagle GB,Olszewski MA,et al.Leptin corrects host defense defects after acute starvation in murine pneumococcal pneumonia[J].Am J Respir Crit Care Med,2006,173(2):212.
  • 7Maya-Monteiro CM,Almeida PE,D'Avila H,et al.Leptin induces macrophage lipid body formation by a phosphatidylinositol 3-kinase-and mammalian target of rapamycin-dependent mechanism[J].J Biol Chem,2008,283(4):2203.
  • 8Mattioli B,Straface E,Quaranta MG,et al.Leptin promotes differentiation and survival of human dendritic cells and licenses them for Th1 priming[J].J Immunol,2005,174(11):6820.
  • 9Mattioli B,Straface E,Matarrese P,et al.Leptin as an immunological adjuvant:enhanced migratory and CD8+ T cell stimulatory capacity of human dendritic cells exposed to leptin[J].FASEB J,2008,22(6):2012.
  • 10Lam QL,Liu S,Cao X,et al.Involvement of leptin signaling in the survival and maturation of bone marrow-derived dendritic cells[J].Eur J Immunol,2006,36(12):3118.

同被引文献46

  • 1Lembo G,Vecchione C,Fratta L,et al.Leptin induces dired vasodilation through distinct endothelial mechanisms[J].Diabetes,2000, 49(2):293-297.
  • 2Quehenberger P, Exner M, Sunder-Plassmarm R, et al .Leptin induces endothelin-1 in endothelial cells in vitro[J].Circ Res,2002,90(6): 711-718.
  • 3Eikelis N,Schlaich M,Aggarwal A,et al.Interactions between leptin and the human sympathetic nervous system[J].Hypertension, 2003,41 (5): 1072-1079.
  • 4Marsh A J,Fontes M A,Killinger S,et al.Cardiovascular responses evoked by leptin acting on neurons in the ventromedial and dorsomedial hypothalamus [J].Hypertension,2003,42(4):488-493.
  • 5Adamczak M,Kokot F,Wiecek AW.Relationship between plasma rennin profile and leptinaemia in patients with essential hypertension[J].J Hum Hypertens,2000,14(8):503-509.
  • 6Schroeter MR,Leifheit M,Sudholt P, et al.Leptin enhances the recruilment of endothelial progenitor cells into neointimal lesions after vascular injury by promoting integrin-mediated adhesion[J]. Circ Res,2008,103(5):536-544.
  • 7Corsonello A,Perticone F, Malara A,et al.Leptin-dependent platelet aggregation in healthy, overweight and obese subjects[J].Int J Obes Relat Metab Disord,2003,27(5):566-573.
  • 8Kang SM,Kwon HM,Hong BK,et al .Expression of leptin receptor (Ob-R) in human atherosclerotic lesions:potential role in intimal neovascularization[J].Yonsei Med J,2000,41(1):68-75.
  • 9Park HY, Kwon HM,Lim HJ,et al.Potential role of leptin in angiogenesis:leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro[J].Exp Mol Med,2001,33(2):95-102.
  • 10Cleland SJ,Sattar N,Petrie JR,et al.Endothelial dysfunction as a possible link between C-reactive protein levels and cardiovascular disease[J].Clin Sci(Lond),2000,98:531-535.

引证文献4

二级引证文献9

重庆医学
2009年 第18期

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