气相色谱法测定二丁基羟基甲苯的含量

Determination of Butylated hydroxytoluene by GC

目的建立二丁基羟基甲苯含量测定方法。方法采用气相色谱法，以4-叔丁酚为内标，色谱柱为DB-624毛细管柱（30m×0．53mm×1μm），汽化室温度220℃，柱温180℃。载气：氮气，5mL·min^-1；检测室温度240℃，尾吹30mL·min^-1。进样量1μL。结果在0．041mg·mL^-1～1．01mg·mL^-1的范围内浓度（C）与峰面积相对响应值（f=A／A内）有良好的线性关系，r=0．9999；样品重复测定的RSD％为1．3％（n=6），日间精密度RSD％为1．2％（n=4）；方法的检测限为1．2μg。结论气相色谱法可以控制二丁基羟基甲苯的含量。

OBJECTIVE To determine butylated hydroxytoluene by GC. METHODS GC was applied to quantitative analysis. Chromatographic conditions were： DB-624 column （30m × 0.53mm × 1μm） ; Flame ionization detector（FID） ; Column temperature： 180℃ ; Injector temperature： 220℃ ; Detector temperature： 240℃ ; Nitrogen was used as carrier gas, the flow rate was 5 mL · min^-1 . An internal standard was 4-tert-butylphehal. RESULTS The calibration curve was linear in the range of 0.041mg· mL^-1 - 1.01mg· mL^-1 . CONCLUSION The GC method can be used as the quality control of butylated hydroxytoluene.