摘要
目的建立通塞脉片中阿魏酸的含量测定方法。方法采用HPLC法，uBondapak C18（4．6mm×250mm），甲醇，25％冰醋酸溶液（35：65）为流动相。检测波长323nm。结果阿魏酸在0．01034—0．1034mg·mL^-1浓度范围内呈良好的线性关系，r=0．9999（n=6）。平均回收率98．68％，RSD为2．09％。结论该法简便、灵敏、准确，可用于通塞脉片的质量控制。
OBJECTIVE To establish a method for the determination of ferulic acid in Shiduqing Capsules. METHODS HPLC method was used in the quantitative analysis using a uBondapak C18（4.6mm × 250mm） column. The mobile phase wasmethyl alcohol-25 % glacial acetic acid （35：65） and detecting wavelength was 323nm. RESULTS The calibration curve was linear in the range of 0. 01034-0. 1034mg· mL^-1 for ferulic acid （r = 0. 9999, n = 6）. The average recovery was 98.68 % and RSD was 2.09 %. CONCLUSION This method is simple, sensitive, accurate and available for the quality control of Tongsaimai Tablet.
出处
《海峡药学》
2009年第8期60-61,共2页
Strait Pharmaceutical Journal
