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荧光原位杂交用于快速产前诊断

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摘要 细胞遗传学分析是目前产前诊断的标准方法,通常首选中期羊膜腔穿刺羊水细胞培养。但该诊断的取材时间受限,培养时间长(7~10d),效率低,技术较难掌握。近年来建立的荧光原位杂交(Fluorescent in situ hybridization,FISH)技术,其应用于未培养的羊水间期细胞,大大提高了诊断效率,只需48h即可给出诊断结果,现将笔者初步经验介绍如下。
作者 苗正友
出处 《浙江医学》 CAS 2009年第5期688-689,共2页 Zhejiang Medical Journal
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参考文献8

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