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不同分期2型糖尿病患者血浆vWF水平变化及与血液流变学指标的相关性 被引量:2

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摘要 目的探讨血浆血管性血友病因子(vWF)水平变化在2型糖尿病(T2DM)疾病进展中的作用。方法对143例不同分期T2DM患者(观察组)和30例健康查体者血浆vWF水平进行了测定,并分析其与血液流变学指标的相关性。结果观察组各期血浆vWF水平及血液流变学指标均显著高于对照组,且随病程进展呈进行性升高;血浆vWF水平与血液流变学各指标均呈显著正相关。结论血浆vWF水平升高可能在T2DM病情进展中起重要作用;监测血浆vWF水平和血液流变学指标对于T2DM慢性微血管病变、血管动脉粥样硬化的预防及早期诊治具有重要意义。
出处 《山东医药》 CAS 北大核心 2009年第27期61-62,共2页 Shandong Medical Journal
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