摘要
目的探讨米托葸醌和阿糖胞苷（MA方案）对急性非淋巴细胞白血病（ANLL）的疗效和应用价值。方法应用MA方案治疗30例ANLL患者，其中米托葸醌10-15mg／d静脉滴注，连续3d；阿糖胞苷100mg，2次／d静脉滴注，连续7d，观察治疗效果和不良反应。结果MA方案治疗初治／复发ANLL患者总有效率为90％，其主要不良反应为骨髓抑制，胃肠道反应，继发感染，脱发和肝功能损害。结论MA方案治疗初治／复发ANLL患者总有效率高，建议临床推广应用。
Objective To explore the effects of mitoxantrone and cytarabine in treatment of acute nonlymphocytic leukemia（ANLL）. Methods A total of 30 patients with ANLL were treated with mitoxantone 10 -15 mg/d for 3 days; cytarabine 200 mg/d for 7 days. The therapeutic efficacy and side effects were observed. Results The total effective rate was 90%. The main side effects were bone marrow depression,gastrointestinal tract response, secondary infection, alopecie and liver damage. Conclusion MA project is effect in treatment of ANLL,which should be suggested in clinical experiences.
出处
《医学综述》
2009年第18期2867-2868,共2页
Medical Recapitulate
