MPV、FIB、ApoAⅠ检测在老年高血压脑梗死患者中的临床意义

Clinical significance of detection of serum FIB,ApoAⅠ and MPV in elderly hypertensive patient complicated with cerebral infarction

目的探讨MPV、FIB、ApoAⅠ等指标在高血压脑梗死患者中的临床意义。方法回顾性分析高血压脑梗死组、单纯高血压组及对照组MPV、FIB、ApoAⅠ、ApoAⅠ/B指标的变化。结果高血压脑梗死组MPV、FIB分别为(13.82±0.73)、(4.19±0.75),明显高于单纯高血压组的(13.22±0.38)、(3.66±0.61)及对照组的(12.41±0.51)、(3.27±0.61),P<0.05;HDL、ApoAⅠ、ApoAⅠ/B分别为(1.02±0.23)、(0.92±0.22)、(0.91±0.24),明显低于单纯高血压组的(1.43±0.31)、(1.26±0.32)、(1.39±0.16)及对照组的(1.61±0.12)、(1.37±0.36)、(1.46±0.21),P<0.05,三组比较具有统计学意义。结论高血压脑梗死患者存在凝血及血脂的异常,早期干预治疗,可减少致残率。

Objective To explore the clinical significance of detection of FIB, ApoA1 and MPV in elderly hypertensive patient complicated cerebral infarction. Methods The clinical changes of MPV, FIB and ApoA I in hypertensive complicated cerebral infarction group, hypertensive group and healthy control group were analyzed. Results MPV and FIB were significantly higher and HDL, ApoA I , ApoA I/B were lower significantly in hypertensive companied with cerebral infarction group than in hypertensive group, healthy control group （P 〈 0.05 ） ;Conclusion The coagulation, anticoagulation and blood -lipid are abnormal in hypertensive companied cerebral infarction group. aoorooriate treatment should be adopted for above abnormality.