纤维支气管镜局部治疗支气管内膜结核的疗效观察

Therapeutic Effect of Bronchial Tuberculosis through Bronchoscope

目的探讨纤维支气管镜下局部治疗支气管内膜结核的疗效。方法对93例确诊的支气管内膜结核患者在全身化疗基础之上依据自愿原则随机分2组,即单纯化疗组、支气管镜下局部注药组进行治疗,并比较两组在痰菌转阴及支气管镜下改变的疗效差异。结果介入化疗组较单纯化疗组治疗后支气管镜下改变有效率高。结论支气管内膜结核经支气管镜介入局部注药有良好的效果,而介入治疗近期疗效更快速有效。

Objective To explore the clinical effects of using bronchoscope to inject drug in thelocation for bronchial tuberculosis （BTB）. Methods BTB patients who were diagnosed and on standard treated were randomly divided into 2 groups, and were combined with the treatment with bronehoscope intervention of drug injection. Efficacy was assessed and followed up after treatment. Results In the local injection group, 1NH and Dexamethasone were used to lavage the focus locally after bronchial secretion was cleaned by hronchoseope. After 1,2,6 months, Interventional chemotherapy group and the treatment of chemotherapy alone group the sputum conversion rate and bronehoscopie changes have efficieney,P values were〈0.01. Concluetion BTB is easily to be miss in the diagnosis, and the treatment outcome of the standard anti BTB treatment was poor. However, the hronehoscope intervention of drug injection are more inexpensive, faster, more effective and safer.