米非司酮配合中药治疗异位妊娠的疗效观察

Observing the therapeutic effect of mifepristone combine with the traditional Chinese medicine on heterotopic pregnancy

目的观察米非司酮结合中药保守治疗异位妊娠的临床疗效。方法将符合保守治疗条件的异位妊娠患者50例随机分成两组:A组(实验组)25例,口服米非司酮300mg,每次50 mg,每日2次口服,共3天,同时给予加服宫外孕二号方加减,每日2次;B组(对照组)25例,单纯服用米非司酮,剂量和用法同A组。观察服药前后血HCG变化及盆腔包块吸收情况,出院后随访3个月。结果两组保守治疗方法成功率分别是,A组保守治疗成功22例(88.0%),治愈天数平均(13.8±2.25)天;B组保守治疗成功18例(72.0%),治愈天数平均(15.6±2.12)天。结论米非司酮配合中药保守治疗异位妊娠,可以有协同杀胚促进炎症包块吸收的作用,提高治愈率,适合基层医院推广。

Objective To investigate therapeutic effect of mifepristone combine with the traditional Chinese medi- cine on heterotopic pregnancy. Methods 50 cases of heterotopie pregnancy patients who were fit for conservative treat- ment were randomly divided into A group （the treatment group, n=25） and B group （the control group, n=25） accord- ing to the random table. The patients of treatment group were treated with mifepristone combine with medicinal broth of heterotopic pregnancy treatment; The control group took mifepristone. Objective the variation of HCG in blood and pelvic cavity clump and follow up visit for 3 months. Results There were obvious differences between treatment group and control group. There were 22 success cases （88.0%）in treatment group and 18 success cases （72.0%）in control group. Average curing days were 13. 8±2.25 in treatment group and 15.6±2. 12 in control group. Conclusion The study showed mifepristone combine with the traditional Chinese medicine treating heterotopic pregnancy may cooperation killing embryo and promote inflammation clump absorbent. Accordingly the cure rate was elevated. The treat method is suitable to be spreaded in primary hospital.