不同浓度的罗哌卡因腰-硬联合麻醉在剖宫产术中的应用

Efficacy of combined spinal epidural anesthesia with different concentration isobaric ropivacaine for caesarean section

目的探讨不同浓度的罗哌卡因腰-硬联合麻醉(CSEA)用于剖宫产术的效果与优缺点。方法健康剖宫产妇200例,随机分为低浓度度小剂量组(L)与等比重常规计量组(N),L组腰麻剂量0.125%罗哌卡因7 ml,N组腰麻剂量0.5%罗哌卡因2 ml。观察麻醉效果、不良反应、应用治疗药物及追加药物的区别。结果麻醉显效时间、镇痛效果两组间无显著性差异,麻醉后低血压、应用治疗药物及追加药物N组均优于L组。结论等比重罗哌卡因腰-硬联合麻醉用于剖宫产术,具有起效快、作用完善、血流动力学稳定的特点。

Objective To investigate the clinical efficacy and security of combined spinal epidural anesthesia （CSEA） with different concentration isobaric ropivacaine for caesarean section. Methods Two hundred healthy caesarean patients were randomly divided into two groups（n= 100）. Group L（low concentration and small dose） and N（isobaric ang general dose） received 7 ml volume of 0. 125 percent ropivacaine and 2 ml volume of 0. 5 percent ropivacaine respectively. Anesthesia effect, side-effect, assistant drugs and additive drug were observed. Results Onset and effect of anesthesia in two groups was nonsignificantly. Onset of hypotension, assistant drugs and additive drug were fewer in group N than in group L（P〈0.01）. Conclusion Combined spinal epidural anesthesia（CSEA） with isobaric 0. 5 percent ropivacaine for caesarean section has characters of quick onset, satisfactory effect and steady circulation.