摘要
新 cerebroside， gynuraoside (1 ) ，从 Gynura divaricata DC 的天线部分被孤立。它决心是 1-O-β； -d-glucopyranosyl-(2S,3S,4R,10E)-2-[(2′R)-2′-hydroxyldocosanoyl-amino]-10-octadecene-1,3,4-triol 根据化学、分光镜的证据。这混合物在 vitro 对 L1210 白血病房间线显示出强壮的 cytotoxicity。
A new cerebroside, gynuraoside （1）, was isolated from the aerial parts of Gynura divaricata DC. It was determined to be 1-0-13- o-glucopyranosyl-（2S,3 S,4R, 10E）-2- [（2＇R）-2^-hydroxyldocosanoyl-amino]- 10-octadecene- 1,3,4-triol on the basis of chemical and spectroscopic evidence. This compound showed strong cytotoxicity against L1210 leukemia cell line in vitro. 2009 Hong Tao Song. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
基金
supported by the Scientific Research Fund of Fujian Provincial Department of Science &Technology(No.2008Y0086)
the Traditional Chinese Medicine Research Fund of Fujian Provincial Public Health Bureau(No.wzy0606),China
