18例胸腹水沉渣包埋切片及免疫组化检查的临床病理分析

Sediments were stainned by immunohistochemical method:a clinicopathologic analysis of 18 Hydrothorax and ascites

目的探讨胸腹水沉渣包埋诊断为恶性肿瘤细胞的临床特征及寻找肿瘤细胞的组织来源。方法通过常规涂片初步筛检18例疑诊恶性肿瘤的标本,经离心沉渣包埋切片,再利用免疫组织化学染色来明确诊断并追朔其组织来源。结果依据18例胸腹水包埋后的组织形态学特征和标记结果证实12例胸腹水样品为腺癌,它们分别是肺泡上皮来源的腺癌、卵巢来源的腺癌及胃肠道来源的腺癌,3例为鳞状细胞癌,2例小细胞神内分泌癌;1例为T细胞性恶性淋巴瘤。结论胸腹水沉渣包埋切片及免疫组化可作为恶性胸腹水诊断的重要手段,为临床寻找和判断恶性肿瘤细胞的组织来源带来实用价值。

Aim To explore, the malignant tumor diagnosis of sediments in hydrothorax and aseites and tumor tissue origin. Method Stainning and diagnosing 18 eases malignant hydrothorax and aseites, we eentrifugated and embedded hydrothorax and aseites, then stained sediments by immunohistoehemieal method. Result By eell morphological characteristics,we diagnosed that 18 eases were ade- noeareinoma, whieh 8 eases deriving from lung cancers and 4 samples from the ovaries and gastrointestinal eareinoma separately. 3 eases squamous were squamous cell carcinoma,2 eases of samples were neuroendoerine eareinoma by the immunohistoehemieal method. The others were separately neuroendoerine carcinoma and T-cell lymphoma. Conclusion Sediment of hydrothorax and aseites and immuno- histoehemieal method were important means for the diagnosis of malignant hydrothorax and aseites and offerring the clinical pratieal value by the morphological eharaeteristies.