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头孢雷特的合成 被引量:1

Synthesis of ceforanide
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摘要 本文创造性地合成了新活性酯8,继而由活性酯8顺利地完成了头孢雷特合成,该法可操作性良好,收率较高,适于大规模制备头孢雷特。 Active ester 8 was prepared creatively and used in the synthesis of ceforanide. Excellent yield and convenient operation made it be suitable to large scale manufacturing.
出处 《中国抗生素杂志》 CAS CSCD 北大核心 2009年第9期553-555,574,共4页 Chinese Journal of Antibiotics
关键词 头孢雷特 合成 活性酯 Ceforanide Synthesis Active ester
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参考文献9

  • 1Integrated res technology llc, Betaines as adjuvants to susceptibility testing and antimicrobial therapy [ P ]. EA002808, 2002.
  • 2Orchid Chemicals & Pharmaceuticals Ltd. , Improved process for the preparation of ceforanide in pure form [ P ]. WO2008010043, 2008,.
  • 3Lim G M F, Endo M, Production of 7-(2-aminomethylphenylacetamido )-3-( 1-carboxymethyltetrazol-5-yhhiomethyl )-3- cephem-4-carboxylic acid [ P ]. Bristol-Mayers Company, US4243803, 1981; US4118563, 1977.
  • 4Sleezer P D, Smith R R. Purification of ceforanide [ P ]. Bristol-Mayers Company, US448958, 1984.
  • 5Brown H C, Suzui A, Sonao S, et al. Reaction of representative organic azides with triethylborane. New route to secondary amines[J]. J Am Chem Soc, 1971, 93, 4329 - 4330.
  • 6Miklos B, Vincent du V. A method of synthesis of long chains using a synthesis of oxytocin as an example [ J ]. J Am Chem Soc, 1959, 81, 5688-5691.
  • 7Miklos B, Vincent du V. Synthesis of a biologically active analog of oxytocin, with phenylalanine replacing tyrosine [ J ]. J Am Chem Soc, 1959, 81,6072 -6075.
  • 8De Tar D F, Delahunty C. Ester aminolysis: new reaction series for the quantitative measurement of steric effects [ J ]. J Am Chem Soc, 1983, 105, 2734 -2739.
  • 9Bashkin J K, Gard J K, Modak A S. Synthesis and characterization of mucleoside peptides: toward chemical ribonucleases[J]. J Org Chem, 1990, 55, 5125 -5132.

同被引文献31

  • 1JoulelA,MiUsK著,业城,高大彬等译.杂环化学[M〕.北京:科学出版社,2004, 590.
  • 2Katritsky AR, Rees CW. Comprehensive Heterocyclic Chemistry: thestructurt, reactions, synthesis and uses of heterocyclic compounds[M]. Vol 5, Part 4A, 1st ed.Oxford:Pergamon Press, 1984,791.
  • 3Su WK, Hong Z, Shan WG, et al. A facile synthesis of 1-substituted-1H-1,2, 3, 4-tetrazoles catalyzed by ytterbium triflate hydrate [J] . EurJ Org Chem, 2006,2006( 12) : 2723-2726.
  • 4Hodges JC, Hamby JM, Blankley JC. Angiotensin II receptor bindinginhibitors [J] . Drugs Fut, 1992, 17(7) :575.
  • 5Conraads VM,Demey HE, Heytens LG, et al. HypoprothrombinemiaDue to Cefamandole (J ] . Klin Wochenschr, 1988, 66 (23): 1190-1192.
  • 6Mendel V, Simanowski Hj, Scholz HC, et al.Therapy with gentam-icin-PMMA beads, gentamicin-collagen sponge, and cefazolin for ex-perimental osteomyelitis due to Staphylococcus aureus in rats [J j .Arch Orthop Trauma Surg, 2005,125(6) :363-368.
  • 7Gundogan N, Citak S, Yucel N, et al. A note on the incidence and an-tibiotic resistance of Staphylococcus aureus isolated from meat andchicken samples[J].Meat Science, 2005,69(4) :807-810.
  • 8周学良主编,项斌,高建荣编.药物〔M〕.北京:化学工业出版社,2002,533-534.
  • 9Wang H, Yu YC, Xie XL, et al. In-vitro antibacterial activities of cef-piramide and other broad-spectrum antibiotics against 440 clinicalisolates in China [J] . J Infect Chemother, 2000, 6(2) :81-85.
  • 10Barry AL, Jones RN, Thornsberry C. Interpretive standards of cefbu-perazone disk diffusion susceptibility tests〔J〕.Eur j Clin Microbiol,1985,4(2):144-145.

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