心脏粘液瘤的病理学研究及其临床意义

Pathologic Study of Cardiac Myxomas and its Clinical Significance

目的探讨心脏粘液瘤的病理形态及其临床意义。方法对４７例手术１１例尸检心脏粘液瘤进行光镜、透射电镜和扫描电镜观察并分析其临床特点。结果（１）心脏粘液瘤是心脏真正的原发性瘤，左心房多见（８２．８％），好发于４０岁以上女性。（２）肿瘤质软易碎的海绵状结构是脱落栓塞的形态学基础。（３）超声心动图有诊断价值，应及时手术，防止并发症。结论心脏粘液瘤的临床表现与病理形态密切相关。

Objective\ To study the pathologic morphology of cardiac myxomas(CM) and its clinical significance.\ Methods\ pathologic study of 47 cases surgically excised and 11 cases at autopsy was performed by light microscopy(LM),transmission(TEM),and scanning electron microscopy(SEM) and their clinical symptoms were analysed.\ Results\ (1)CM are the most common primary tumors and spongelike architecures are morphologic basis for embolization.\ (2)Echocardiography is an available tool for diagnosis,surgical excision should be performed without delay to prevent embolization.\ Conclusion\ There are close relationships between the tumor quality and clinical manifestation.