243例太田痣临床分析

Clinical analysis of 243 eases of nevus of Ota

目的对湖北及周边地区太田痣患者进行临床分析。方法回顾分析243例太田痣患者在发病时间、色素性疾病家族史及患者母亲妊娠期间是否有用药史等方面进行统计学比较。结果太田痣出生时发病者占58．0％，出生后发病者占42．0％，主要集中于5～15岁。有色紊性疾病家族史者占60．1％，其中以雀斑和咖啡斑为主。患有太田痣与女性妊娠期间是否有用药史无明显关系。结论太田痣可能具有遗传性，具有色素性疾病史的患者，其后代患太田痣的可能性较大。

Objective To study the clinical features of nevus of Ota in patients from Hubei Province and adjacent areas. Methods A retrospective study was performed to assess the onset age of disease, family history of pigmentary diseases, medication use during pregnancy, etc, of 243 patients with nevus of Ota from Hubei Province and adjacent areas. Results Of the 243 patients, 58% were born with a lesion of nevus of Ota, 42% developed eruptions postnatally （mainly between the age of 5 to 15 years）. Family history of pigmentary diseases was observed in 60% of these patients, and in these pigmentary diseases, freckles and cafe-au-lait spots predominated. There was no significant correlation between the development of this disease and history of taking medicine during pregnancy. Conclusions Nevus of Ota may be a hereditary disease, and patients with pigmentary disorders are more likely to have descendants with nevus of Ota.