不同MRI序列在显示颞叶内侧硬化的对照研究

Comparison of different MRI sequences in mesial temporal sclerosis

目的比较各序列在颞叶内侧硬化病人显示海马信号强度增加的作用。材料与方法对３０例临床及脑电图或脑地形图诊断为颞叶癫痫的病人采用双回波常规自旋回波（ＳＥ）序列、快速自旋回波（ＦＳＥ）序列和液体衰减反转恢复（ＦＬＡＩＲ）序列进行ＭＲＩ检查，并通过目测观察和信号强度测量等方法对图像进行处理。结果ＳＥ序列质子密度加权像判别海马信号强度增加的准确度最差（４３．３％）；ＦＳＥ序列次之（６２．２％）；ＳＥ序列Ｔ２加权像和ＦＬＡＩＲ序列判别海马信号强度增加的准确度很高，且ＦＬＡＩＲ序列（８８．９％）较ＳＥ序列Ｔ２加权像（７７．８％）更为准确。

Purpose To compare the efficacy of fast spin echo(FSE)imaging, fluid attenuated inversion recovery(FLAIR) imaging and double echo conventional spin echo (SE) imaging in identification of increased hippocampal signal intensity associated with mesial temporal sclerosis(MTS). Materials and methods MR scans of 30 patients with temporal lobe epilepsy proven by clinical history and electroencephalogram(EEG) were assessed for the presence of increased hippocampal signal intensity. Results The accuracy for detecting increased hippocampal signal intensity with different MR pulse sequences was FLAIR sequence(88.9%), SE (77.8%), FSE (62.2%), and proton density sequence(43.3%), in decreasing order of frequency. Conclusion FLAIR sequence provides imaging with T 2 weighted contrast and complete suppressing of high signal intensity of CSF. FLAIR may become a routine MR sequence to replace SE T 2WI or proton density weighted imaging(PDWI) for evaluation of MTS.