油性中药抗癌剂OCC肝动脉栓塞治疗肝癌84例3年随访报告

Oleum Curcuma Compound Used in Hepatic Arterial Embolization to Treat Hepatocellular Carcinoma: Follow up Report of 84 Cases

目的：考查中药抗癌剂复方莪术油肝动脉栓塞治疗肝癌的疗效和意义。材料与方法：用莪术油、鸦胆子油和碘油配制成复方莪术油，经肝动脉栓塞治疗８４例原发性肝癌。结果：治疗后肿瘤平均缩小率３９．２％。１、２、３年生存率分别为８０％、４３．４％和２４％。无因治疗引起肝功恶化和骨髓抑制现象。部分患者治疗后肝功能明显改善。结论：复方莪术油作为一种新的中药肝动脉栓塞剂，治疗肝癌具有肯定的疗效。这种油性中药制剂具有抗癌、低毒、栓塞和留滞于肿瘤局部的突出特点。

Objective: To investigate the effect of the oleum of curcuma compound (OCC), a anticancerous agent of traditional chinese medicine, in the treatment of hepatocellular carcinoma (HCC) through transhepatic arterial embolization (TAE).Materials and Methods:OCC which was made by the mixed oleum of curcuma zedoama, oleum of Brucea javanica and lipiodol was injected through hepatic artery by catheter to treat 84 patients with HCC.Results:After treatment, the tumors were shrunk 39.2% averagely. 1, 2, 3 year survival rates were 80%, 43.4% and 24% respectively. NO liver function worsening and marrow depression caused by the treatment were found.Conclusion: OCC has a definite effect in treatment of HCC by TAE. As a oily anticancerous agent of traditional chinese medicine, Its conspicuous characteristic include low toxicity, embolizability and remainability in tumor tissue so, it has a great superiority to become a satisfactory embolic agent for the treatment of HCC.