变应性鼻炎动物模型的研究进展

Experimental animal models of allergic rhinitis and evaluation

变应性鼻炎是一种变态反应性疾病，是全身变应性炎症的局部反应，发病率高，发病机制复杂，因此，建立能够较好的模拟人类变应性鼻炎的动物模型有助于对其发病机制和治疗进行深入研究。目前，已经建立了多种变应性鼻炎的动物模型。本文就用各种动物建立的变应性鼻炎模型作如下综述。

Allergic rhinitis is an allergic disease, which is a local reaction of the whole body. It has high incidence and complex pathogenesis. The establishment of animal modesl which is well simulated to the human＇s allergic rhinitis is helpful for us to study the pathogenesis and the treatment of allergic rhinitis more clearly. Many animal models of allergic rinitis have been found until now. This article reviewes the different animal models with allergic rhinitis.