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左炔诺孕酮宫内缓释系统临床应用研究 被引量：6

Clinical Applications Research of Levonorgestrel-releasing Intrauterine System
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摘要 左炔诺孕酮宫内缓释系统(LNG-IUS)是一种安全、高效的宫内节育器(IUD),其通过每天释放小剂量的左炔诺孕酮至宫腔实现孕激素的非全身给药,从而开辟了在非避孕领域的许多新的应用。现就其在治疗月经过多、子宫内膜异位症和腺肌症、激素替代治疗期间的子宫内膜保护等方面进行综述。 Levonorgestrel-releasing Intrauterine System （LNG-IUS） is a safe and highly efficient intrauterine device（IUD）.Many new applications in non-contraceptive fields have been developed through its non- systemic administration of progestogen by daily releasing low dose of LNG into uterine cavity.This article reviews its applications in the treatment of menorrhagia, endometriosis and adenomyosis as well as the endometria protection during hormone replacement therapy（HRT）.
作者 楚素伟 郎玉萍
机构地区 天津市中心妇产科医院
出处 《国际生殖健康／计划生育杂志》 CAS 2009年第5期317-319,共3页 Journal of International Reproductive Health/Family Planning
关键词 左炔诺孕酮宫内缓释系统 月经过多 子宫内膜异位症 子宫腺肌病 激素替代治疗 LNG-IUS Menorrhagia Endometriosis Adenomyosis Hormone replaeementtherapy
分类号 R169.42 [医药卫生—公共卫生与预防医学]
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参考文献20

  • 1Blumenthal PD, Trussell J, Singh RH, et al. Cost-effectiveness of treatments for dysfunctional uterine bleeding in women who need contraception [J]. Contraception, 2006, 74(3):249-258.
  • 2Reid PC, Coker A, Cohart R. Assessment of menstrual blood loss using a pictorial chart: a validation study [J]. BJOG, 2000, 107 (3): 320-322.
  • 3Pakarinen P, Luukkainen T. Treatment of menorrhagia with an LNGIUS [J]. Contraception, 2007, 75(6 Suppl):S118-122.
  • 4Reid PC, Virtanen-Kari S. Randomised comparative trial of the levonnrgestrel intrauterine system and mefenamic acid for the treatment of idiopathic menorrhagia: a multiple analysis using total menstrual fluid loss, menstrual blood loss and pictorial blood loss assessment charts [J]. BJOG, 2005, 112(8):1121-1125.
  • 5Andrade A, Wildemeersch D. Menstrual blood loss in women using the frameless FibroPlant LNG-IUS [J]. Contraception, 2009, 79(2): 134-138.
  • 6You JH, Sahota DS, Moyuen P. A cost-utility analysis of hysterectomy, endometrial resection and ablation and medical therapy for menorrhagia [J]. Hum Reprod, 2006, 21(7):1878-1883.
  • 7Barrington JW, Arunkalaivanan AS, Abdel-Fattah M. Comparison between the levonorgestrel intrauterine system (LNG-IUS) and thermal balloon ablation in the treatment of menorrhagia [J]. Eur J Obstet Gynecol Reprod Biol, 2003, 108(1): 72-74.
  • 8Bahamondes L Petta CA, Fernandes A, et al. Use of the levonorgestrelreleasing intrauterine system in women with endometriosis, chronic pelvic pain and dysmenorrhea [J]. Contraception, 2007, 75 (6 Suppl): S134-139.
  • 9Fedele L, Blanchi S, Raffaelli R, et al. Treatment of adenomyosisassociated menorrhagia with a levonorgestrel-releasing intrauterine device [J]. Fertil Steril, 1997, 68(3): 426-429.
  • 10Bragheto AM, Caserta N, Bahamondes L, et al. Effectiveness of the levonorgestrel-releasing intrauterine system in the treatment of adenomyosis diagnosed and monitored by magnetic resonance imaging [J]. Contraception, 2007, 76(3): 195-199.

同被引文献36

引证文献6

二级引证文献25

国际生殖健康／计划生育杂志
2009年 第5期

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