不伴随糖尿病和高血压的肥胖妇女尿微量白蛋白的调查

Investigation of Microalbuminuria in Nondiabetic,Normotensive Obese Women

目的:调查不伴随糖尿病和高血压的肥胖妇女与尿微量白蛋白是否有相关性;方法:57位来肥胖女性和30位年龄相当的健康女性入选为本研究对象。记录BMI、腰围和血压,用散射比浊的原理测定尿微量白蛋白,同时测定尿肌酐含量用来排除水合作用的影响。结果:肥胖组和对照组尿微量白蛋白排泄值无显著性差别。尿微量白蛋白与BMI、腰围、腰围臀围比值以及血压无相关性。结论:不伴随糖尿病和高血压的肥胖妇女尿微量白蛋白含量很低,肥胖组和对照组尿微量白蛋白排泄值无显著性差别。

Objective：To investigate if obesity which is not accompanied by diabetes and/or hypertension is associated with microalbuminuria in female patients. Methods A total of 57 obese female patients and 30 age-matched, lean, healthy women were enrolled in the study. Body-mass index （BMI） , waist circumference, waist/hip ratio （WHR） and systolic and diastolic blood pressures were recorded. Albumin excretion in random urine samples （UAE） were measured Results The albumin excretion in random urine sample was similar in obese and control groups （2.01±1.69mg/ mmoL vs 1.64±0.70 mg/mmoL p〉0.05） . There were no correlations between the albumin excretion and BMI, Waist circumference, WHR, systolic or diastolic blood pressure. Conclusions Microalbuminuria was not detected in obese women without diabetes and/or hypertension and UAE was similar in obese and lean women.