415份痰标本的病原菌鉴定及药敏结果分析

Identification of Pathogens and Drug Sensitivity Analysis 415 Sputum Samples

目的了解医院肺部感染患者痰病原菌菌谱的分布及其耐药机制、合理指导临床应用抗菌药物,有效防止医院感染的发生。方法对患者痰液分离出的病原菌用微量生化编码鉴定管进行鉴定,采用临床常用抗菌药物进行药物敏感试验。结果从415例呼吸系统患者痰标本检出病原菌537株,革兰阳性球菌占70.8%、革兰阴性杆菌占28.1%、真菌占1.1%;其中检出MRSA18株和ESBLs菌6株。结论对于肺部患者的抗感染治疗,临床上应重视痰培养检查,明确感染病原菌的种类和药敏结果,以合理使用抗菌药物提高疗效。

OBJECTIVE To understand the bacterial spectrum distribution of sputum among the lung infection patients in our hospital and their resistance mechanisms for the reasonable clinical application of antibiotics to effectively prevent the occurrence of nosocomial infections. METHODS The pathogens isolated from the sputum of patients were identified with pathogen micro-biochemical identification code and the commonly used antibiotics were detected by drug sensitivity tests. RESULTS From 415 samples of the sputum, 537 strains were detected out, from them Gram-positive cocci accounted for 70. 8%, Gram-negative bacteria accounted for 28.1%, and Candida albicans accounted for 1. 1% MRSA was in 18 strains and ESBLs 6 strains. CONCLUSIONS It is important to sputum culturing for lung infection patients and determining the pathogen species and in their drug susceptibility results, the in order to rationally use the antibiotics and enhance the effectiveness of treatment.