广东省12种宫内节育器致子宫异常出血的对比研究

Comparative Study on Metrorrhagia Induced by Twelve Kinds of IUDs in Guangdong Province

目的:评价广东省使用率较高的12种宫内节育器(IUD)放置后因出血取出情况。方法:采用分层整群随机抽样方法,随机抽查2000年1月1日～2007年6月30日省内放置IUD的育龄妇女,包括已取出IUD和正在使用者。对入选人群36个月内月经改变及因出血IUD累积取出率进行分析。结果:月经量增多发生率母体乐39.24%,高支撑力含铜34.53%,曼月乐10.21%;点滴出血发生率高支撑力含铜19.23%,爱母17.89%,元宫型药铜9.52%;因出血取出率母体乐14.6%,高支撑力含铜13.6%,元宫型药铜0.8%,曼月乐0.0%,各项差异均有统计学意义(P<0.01)。结论:12种IUD中,母体乐及高支持力含铜IUD 36个月内因出血累积取出率最高,而曼月乐、元宫药铜IUD因出血累积取出率最低。

Objective ： To evaluate the situation of IUD removal for the metrorrhagia after placement of twelve kinds of IUDs applied frequently in Guangdong province. Methods： Stratified cluster random sampling method was adopted, and the reproductive aged women who were placed IUD from 1 st Jan, 2000 to 1 st May, 2007, including the subjects with IUD removal and IUD usage, were examined randomly. The accumulated removal rates of IUD for the change of menstruation within 36 months and vaginal bleeding were analyzed. Results： The incidences of increased menstrual blood volume were 39.24% （Mutile IUD） , 34.53% （IUD with high holding power）, and 10.21% （Manyuele IUD）, respectively. The incidences of spotting bleeding were respectively 19.23% （IUD - Cu with high holding power）, 17.89% （Aimu IUD）, and 9.52% （ YGCu IUD）. The removal rates of IUD for bleeding were 14.6% （ Mutile IUD）, 13.6% （ IUD with high holding power）, 0.8% （YGCu IUD）, and 0.0% （Manyuele IUD）, respectively. All differences among each group were statistically significant （P 〈0.01 ）. Conclusion： Among the twelve kinds of IUDs, the accumulated removal rates of Mutile IUD and IUD - Cu with high holding power are relative higher for the vagi- nal bleeding within 36 months, while Manyuele IUD and YGCu IUD have relative lower removal rates.