胰岛素强化治疗肝移植术后糖尿病

Intensive insulin therapy for post-transplant diabetes mellitus in liver transplantation

目的:观察胰岛素强化治疗肝移植后糖尿病的疗效。方法:对2004年2月至2008年3月21例确诊肝移植术后糖尿病患者予胰岛素强化治疗2～4周。结果:21例患者治疗结束时血糖均控制理想,空腹及餐后2h血糖均较治疗前明显降低(P<0.05)。结论:对肝移植后糖尿病患者予胰岛素强化治疗,可以有效控制高血糖。

Objective To investigate the efficacy of intensive insulin therapy for post-transplant diabetes mellitus （PTDM） in liver transplantation. Methods From February 2004 through March 2008, 21 patients with clinically confirmed PTDM received intensive insulin therapy for 2 to 4 weeks. Results Blood sugar levels were controlled ideally in all the patients after completion of the therapy. As compared with the baseline, fasting and 2-hour postprandial sugar levels were markedly declined （P 〈 0.05）. Conclusions Intensive insulin therapy can effectively control hyperglycemia in patients with post-transplant diabetes mellitus.