高频电波刀宫颈环切术治疗CIN的临床分析

Clinical analysis in the treatment of CIN with Leep

目的探讨高频电波刀宫颈环切术(1oop electrosurgical excision procedure,Leep)治疗宫颈上皮内瘤样病变(Cervical Intraepithelial Neoplasia,CIN)的临床效果。方法经宫颈细胞学检查和阴道镜下多点活检病理诊断为CIN的患者120例进行回顾性研究,随机分成Leep治疗组(80例)及激光对照组(70例),比较两组手术时间、术中出血量、治愈率及术后并发症。结果二者在手术时间、术中出血,Leep组明显优于激光组(P<0.01);术后半年治愈率Leep组96.52%(77/80),激光对照组97.14%(68/70),差异无显著性(P>0.05)。结论Leep刀治疗优于激光治疗,是治疗CIN的有效方法,对其可靠性尚待进一步研究。

Objective To investigate the clinical value of Leep in treatment of CIN. Methods By cervical cytology and multi-point biopsy under colposcopy of 120 patients diagnosed as CIN through pathology were analized retrospectively, patients were randomly divided into Leep treatment group （80 cases） and control group of laser treatment （70 cases ）. Compared surgical time, bleeding volume, cure rate and postoperative complications of two groups. Results Both in the operation time and blood loss, Leep was significantly better than the laser group （P 〈0.01）. after six months, the cure rate of Leep group and laser control group were 96. 52% （77/80） and 97.14% （68/70） respectively, but there was no significant difference （P 〉 0. 05）. Conclusion Leep treatment is superior to laser treatment, Leep treatment of CIN is an effective method, however its reliability has to be studied further.