呼吸内科患者病原菌分布及耐药分析

目的了解呼吸内科呼吸道感染住院患者病原体分布及耐药,给临床诊治提供参考。方法分析从2005～2007年医院呼吸内科下呼吸道感染患者痰标本分离出的病原菌及耐药情况。结果革兰氏阴性杆菌占70.5%,依次为肺炎克雷伯菌、铜绿假单胞菌、大肠埃希菌和不动杆菌属等,革兰阳性球菌占18.5%,真菌占11%。革兰阴性杆菌对美洛培南、阿米卡星、头孢哌铜/舒巴坦较敏感,革兰氏阳性球菌对万古霉素、利福平、阿米卡星较敏感。结论呼吸道感染病原菌以革兰阴性杆菌占优势,各种菌对抗生素均呈不同程度耐药,临床用药应参考检验结果合理使用抗生素。

Objective To analyse the resistance of pathogenic bacteriu induceing respiratory infection. Methods By the retrospective methods,we analyzed the pathogens isolated from the aputa of the hospitalized patients with lower respiratory tract infection in the department of respiratory medicine from 2005 to 2007 and their drug resistance. Results There were 70. 5% strains of Gram-negative bacilli, 18. 5% strains of Grampositive bacteria and 11% strains of fungi. The most important Gram-negative pathogens were Klebsiella pneumoniae, Pseudomonas aeruginosa, Eseheriehia coli and Acinetobaeter . Strains of Gram-negative bacteria were susceptible to MPN, CFP/SU and AN, strains of Gram-positive pathogens were susceptible to VA, RA and AN. Conclusions The attention to the change of pathogenic bacterium in respiratory infection and the resistance to antibilties, making good use of antibiotics could provide some evidence for clinic.