ComplexonⅢ、Ⅳ及HMP-Na对胆石金属元素影响的实验研究

Experimental Studies of Influences of Complexon Ⅲ, Ⅳ and HMP-Na on Metallic Elements of Cholelith

本文对30例胆石标本用2%EDTA、2%CDTA、5%HMP—Na、去离子水作用6h后,离心,弃去上层清液,将残渣充分消解后用GGX—1型原子吸收分光光度计测定Ca、Mg、Cu、Fe、Mn、Zn含量,并以未处理组作对照。结果表明5%HMP—Na能较好地络合胆色素结石中的上述金属离子,为临床溶石治疗应用理想的络合剂提供了实验依据。

Although the efficacy of complexon Ⅲ (EDTA), complexon Ⅳ (CDTA) and HMP-Na (hexametaphosphate) as complex compounds of metallic elements of cholelith has been reported in many papers, it is still a question on deciding which is the best one. This article describes an experimental study of comparing the influence of 2% EDTA. 2% CDTA, 5%HMP—Na and deionic water on Ca, Mg, Cu, Fe, Mn and Zn of 30 cholelith samples. These elements were measured with atomic absorption spectroscopy. The results were compared to the group which was not treated. Our results demonstrate that 5% HMP-Na is the best complex compound for metallic elements of a pigment stone. This study provides an experimental basis for using an ideal complex compound in clinic to dissolve bile pigmental stones.