Toll样受体与间充质干细胞的研究进展
摘要
间充质干细胞(mesenchymal sterncells,MSCs)是中胚层来源的一种成体干细胞,具有诱导分化为多种成体细胞如脂肪、成骨、软骨、肌肉、神经、内皮等细胞的功能。此外,MSCs还可支持和调节造血细胞生成,改变造血微环境,参与炎症、外伤等引起的损伤修复。近年来的研究显示,MSCs有免疫调节作用,可抑制T淋巴细胞、B淋巴细胞[1]及自然杀伤(NK)细胞的免疫反应口,
出处
《中华风湿病学杂志》
CAS
CSCD
北大核心
2009年第9期638-641,共4页
Chinese Journal of Rheumatology
基金
江苏省“科技兴卫”工程项目(RC2007002)
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