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帕金森病运动并发症中非药物性影响因素的系统评价 被引量：3

Non-pharmacological influencing factors of motor complications in Parkinson＇s disease： a systematic review
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摘要 目的系统评价帕金森病（PD）运动并发症的非药物性影响因素。方法通过Medline、Embase、Cochrane Database、万方数据库，检索国内外至2008年8月前已发表的关于PD异动症（DK）或症状波动（MF）影响因素的前瞻性及回顾性研究，对所纳入文献进行评价。结果起病年龄早、女性患者，病程长可能是运动并发症发生的危险因素。结论需要更多高质量的研究，进一步对影响PD运动并发症的因素做出评估。 Objective To make a systematic review of risk factors associated with motor complications in Parkinson＇s disease（PD）. Methods Medline, EMbase and Cochrane Database were used to search for prospective and retrospective studies on the factors associated with dyskinesia and motor fluctuations. Methodological quality was checked by two independent reviewers. Results Earlier age at onset, female gender and a long disease duration might be the risk factors of motor complications. Conclusion More high-quality clinical trials are required to evaluate the factors associated with motor complications.
作者 刘振国 周明珠 陈伟
机构地区 上海交通大学医学院附属新华医院神经科
出处 《中华医学杂志》 CAS CSCD 北大核心 2009年第33期2324-2328,共5页 National Medical Journal of China
基金 教育部留学回国人员科研启动基金 上海市教育委员会基金（06BZ048） 上海市浦江人才计划 卜海市科委上海-飞利浦研究与发展基金合作基金（07SP07005）
关键词 帕金森病 异动症 危险因素 系统评价 Parkinson＇s disease Dyskinesias Risk factors Systematical review
分类号 R686 [医药卫生—骨科学]
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参考文献18

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  • 2周明珠,刘振国,陈伟,陆丽霞,吴佳英,戚辰.多巴胺能药物治疗对帕金森病运动并发症影响的系统评价[J].中华医学杂志,2009,89(7):438-444. 被引量：6
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二级参考文献28

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共引文献5

同被引文献37

  • 1巴茂文,刘振国,孔敏,杨红旗,陈生弟,陆国强.左旋多巴诱发帕金森病大鼠异动症模型的建立和评价[J].上海交通大学学报（医学版）,2006,26(7):810-812. 被引量：15
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引证文献3

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中华医学杂志
2009年 第33期

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