期刊文献+

轮状病毒肠道外感染发病机制的研究进展 被引量:5

Progress in pathogenesis of extraintestinal rotavirus infection
原文传递
导出
摘要 轮状病毒是一种双链RNA病毒,其基因序列已经基本查明。它是引起婴幼儿严重腹泻最常见的病原体,不仅可以引起胃肠道疾病,还可导致全身各个脏器的病变,发病机制和多个因素有关。肠道外发病可能是免疫功能异常(或正常)的情况下,轮状病毒穿透胃肠道屏障通过血液播散,感染肠道外多个器官所致。
出处 《国际儿科学杂志》 2009年第5期513-515,共3页 International Journal of Pediatrics
基金 基金项目:安徽省教育厅自然科学研究项目(2006KJ107C)
  • 相关文献

参考文献23

  • 1Obert G, Peiffer I, Servin AL. Rotavirus-induced structural and functional alterations in fight junctions of polarized intestinal Caco-2 cell monolayers. J Virol,2000,74(10) :4645-4651.
  • 2Lorrot M, Vasseur M. How do the rotavirus NSP4 and bacterial enterotoxins lead differently to diarrhea? Virol J,2007,4:31.
  • 3Berkova Z,Crawford SE,Blutt SE,et al.Expression of rotavirus NSP4 alters the actin network organization through the actin remodeling protein eofilin. J Virol, 2007,81 (7) : 3545-3553.
  • 4Blutt SE,Kirkwood CD,Parreno V,et al.Rotavirus antigenaemia and viraemia:a common event? Lancet,2003,362(9394) : 1445-1449.
  • 5Lynch M, Shieh WJ, Tatti K, et al. The pathology of rotavirus associated deaths, using new molecular diagnostics. Clin Infect Dis, 2003,37 (10) : 1327-1333.
  • 6Chiappini E,Azzari C,Mofiondo M,et al.Viraemia is a common finding in immunocompetent children with rotavims Infection. J Med Virol, 2035,76 (2) : 265-267.
  • 7Azevedo MS,Yuan L,Jeong Kl,et al.Viremia and nasal and rectal shedding of rotavirus in gnotobiotic pigs inoculated with Wa human rotavirus. J Virol, 2005,79 ( 9 ) : 5428 -5436.
  • 8Crawford SE,Patel DG,Cheng E,et al. Rotavirus viremia and extraintestinal viral infection in the neonatal rat model. J Virol,2006,80(10) :4820-4832.
  • 9Blutt SE,Conner ME.Rotavirus:to the gut and beyond. Curr Opin Gastroenterol, 2007,23(1) :39-43.
  • 10Fenaux M,Cuadras MA,Feng N,ct al.Extraintestinal spread and replication of a homologous EC rotavirus strain and a heterologous rhesus rotavirus in BALB/c mice. J Virol,2006,80( 11 ) : 5219-5232.

二级参考文献13

共引文献50

同被引文献103

引证文献5

二级引证文献32

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部