北京市空气污染水平对出租车司机心血管系统相关血液指标的影响

Effect of Ambient Air Pollution on Cardiovascular Related Blood Indicators in Taxi Drivers

目的探讨北京市空气污染水平对职业高暴露人群(出租车司机)心血管系统相关血液指标的影响。方法以14名<45岁、健康、不吸烟的出租车司机为研究对象,在2008年春季(4月15—16日)和秋季(9月17日)分别采集其血液,检测心血管系统相关血液指标(包括高敏C反应蛋白、血脂和血液流变学指标)的水平,同时收集2次采血日期前3个月的每日空气污染指数,以比较不同空气污染水平对出租车司机心血管系统相关血液指标的影响。结果北京市2008年春季空气污染水平明显高于秋季。在空气污染水平较高的春季,出租车司机血浆黏度水平较高,高密度及低密度脂蛋白的水平较低;在空气污染水平较低的秋季,出租车司机血浆黏度水平较低,高密度及低密度脂蛋白的水平较高。结论出租车司机高密度及低密度脂蛋白与空气污染水平之间存在负关联,血浆黏度与空气污染水平之间存在正关联。

Objective To estimate the effect of ambient air pollution on cardiovascular related blood indicators in occupational, highly-exposed population in Beijing. Methods The blood samples were collected for twice from 14 taxi drivers in spring （15-16 April） and autumn （17 September） of 2008, respectively. The air pollution index before the sampling days was also collected for three months in each season. Results Ambient air quality was better in autumn than spring of 2008. The level of plasma viscosity was lower and levels of low-/high-density lipoproteins were higher in autumn compared with those of taxi drivers in spring. Conclusion Air pollution is positively associated with plasma viscosity and negatively associated with low-/high-density lipoproteins in occupational, highly-exposed individuals.