拟除虫菊酯类农药对典型冷-温血动物毒性作用研究进展

Research Progress on Toxicity of Pyrethroid Pesticide to Typical Animals

目前,合成杀虫剂拟除虫菊酯类农药被广泛应用于农业生产与日常生活中。大部分拟除虫菊酯类农药属于环境激素类物质,长期接触会引起动物和人类产生不良反应,甚至诱发致畸、致癌、致突变作用。笔者选取健康风险评价中的典型动物——鱼类、小鼠和大鼠,综述了拟除虫菊酯类农药的神经毒性、生理生化毒性、生殖毒性以及对生物酶和免疫系统的影响。

Synthetic pesticides-pyrethroids have been widely used in agriculture and in households. Most of them are the environmental hormone substances. Pyrethroids have toxic effects on animals and humans, inducing teratogenicity, carcinogenicity and mutagenicity. In the present paper, the typical animals -fish, mice and rats were choosen for the health risk assessment, and the research progresses on adverse effects of pyrethroids in nervous toxicology, physiological and biochemical toxicology, reproductive toxicology were summerized, as well as the effects of the animal enzymes and immune system.